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Kikuchi-Fujimoto Disease

Kikuchi-Fujimoto Disease:

A 32-year-old man from Visakhapatnam, who had recurrent lymph node swelling for nearly six years and was repeatedly treated for suspected tuberculosis, has finally been diagnosed with rare Kikuchi–Fujimoto disease recently.

  • Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenopathy, is a rare inflammatory disorder of the lymph nodes.
  • It causes swollen, painful lymph nodes that most often develop in neck (cervical lymphadenopathy), along with fever and fatigue.
  • It most often affects people aged 30 and under.
  • It can closely mimic tuberculosis and lymphoma.
  • The cause of KFD remains unclear, but both viral infections and autoimmune mechanisms have been suggested as potential triggers.
  • Usually, this disease does not cause severe problems and gets better on its own.
  • However, in some people, it can be associated with autoimmune disorders, conditions where the immune system mistakenly attacks the body’s cells and tissues.]
  • There isn’t a specific cure, but certain medication can help to relieve symptoms, including:
  • NSAIDs (nonsteroidal anti-inflammatory drugs), for fever, pain, and headache.
  • Corticosteroids may be used in severe cases to reduce swelling in lymph nodes.