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Autoimmune Blistering Diseases

Autoimmune Blistering Diseases:

A joint study by Punjabi University, Patiala, and PGIMER, Chandigarh, has developed artificial intelligence-based methods to aid diagnosis of Autoimmune Blistering Diseases (AIBDs).

  • Autoimmune Blistering Diseases (AIBDs), also called autoimmune bullous disorders, are a group of rare skin diseases.
  • They happen when immune system attacks skin and mucous membranes — the lining inside mouth, nose, and other parts of body. This causes blisters to form.
  • The places on body where blisters form depend on which disorder one has.
  • Some AIBDs cause blisters to grow on the skin.
  • Other types cause them to form in the mucous membranes that line the mouth, nose, throat, eyes, and genitals.
  • They can be painful or itchy. They can break open and leave a sore.
  • Although rare, AIBDs can be severe and even life-threatening if untreated because of:
    • Extensive skin loss
    • Secondary infections
    • Nutritional deficiencies
    • Damage to mucous membranes and eyes
  • Treatment aims to suppress the abnormal immune response and prevent new blister formation:
    • Corticosteroids
    • Immunosuppressive drugs
    • Biologic therapies such as Rituximab
    • Wound care and infection prevention