Chlorpheniramine and Phenylephrine Combination:
The Union Health Ministry has tightened rules for FDCs containing chlorpheniramine maleate and phenylephrine, requiring labels to warn against their use in children below four years.It is an over-the-counter and prescription Fixed-Dose Combination (FDC) commonly formulated as oral drops, syrups, and tablets for symptomatic relief of common cold, allergic rhinitis, and upper respiratory tract congestion. It combines two active pharmacological agents:Chlorpheniramine Maleate: A first-generation antihistamine that blocks H1 histamine receptors to alleviate sneezing, watery eyes, and a runny nose.Phenylephrine Hydrochloride: A sympathomimetic nasal decongestant that constricts dilated blood vessels in the nasal passages to relieve stuffiness.
