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Naegleria fowleri

Naegleria fowleri:

Scientists have figured out how Naegleria fowleri amoebae go from the nose to the brain, with N. gruberi as a proxy.

  • Naegleria fowleri is commonly known as “brain-eating amoeba,” is a single-cell organism.
  • It thrives in warm freshwater lakes, ponds and rivers. It can also survive in poorly maintained swimming pools in rare cases.
  • Only one species of Naegleria, Naegleria fowleri, infects people.
  • It causes Primary amoebic meningoencephalitis or PAM.
  • It is typically acquired through the nasal passage and mouth.
  • The amoeba then migrates through the olfactory nerve to the brain, where it causes severe inflammation and destruction of brain tissue.
  • The Naegleria fowleri infection does not spread from person to person, nor does it manifest symptoms when contracted in other forms.
  • The infection is primarily associated with a warm freshwater environment, especially during hot summer months when water temperatures are higher.
  • Primary Amoebic Meningoencephalitis is caused by Naegleria fowleri.
  • It is non-communicable and people cannot get infected with Naegleria fowleri from drinking water contaminated with the amoeba.
  • There are no effective treatments for the disease yet.
  • At present, doctors treat it with a combination of drugs, including amphotericin B, azithromycin, fluconazole, rifampin, miltefosine, and dexamethasone.