Extrachromosomal DNA (ecDNA):
Extrachromosomal DNA (ecDNA) has emerged as a groundbreaking area in cancer biology, challenging foundational genetic principles and offering new insights into cancer progression and drug resistance.ecDNA is a circular fragment of genetic material that breaks away from chromosomes and floats freely in the cell nucleus.Created by DNA damage, chromosomal rearrangements, or errors during cell replication.