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Extrachromosomal DNA (ecDNA)

Extrachromosomal DNA (ecDNA):

Extrachromosomal DNA (ecDNA) has emerged as a groundbreaking area in cancer biology, challenging foundational genetic principles and offering new insights into cancer progression and drug resistance.ecDNA is a circular fragment of genetic material that breaks away from chromosomes and floats freely in the cell nucleus.Created by DNA damage, chromosomal rearrangements, or errors during cell replication.