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Lathyrism : Neurological Disease

Lathyrism : Neurological Disease

Grass pea, also known as khesari dal, has been historically infamous for causing lathyrism, a neurological disease leading to lower limb paralysis.

  • In the late 19th century, an outbreak of lathyrism linked to grass pea led to its ban in India in 1961 under the Prevention of Food Adulteration Act.
  • Despite the ban, grass pea cultivation continued, and researchers developed low-toxin varieties.
  • In 2015, an expert committee recommended lifting the ban, emphasizing its potential for food security amid climate change.
  • Lathyrism is a neurological disorder caused by eating too much grass pea (Lathyrus sativus).
  • It’s also known as neurolathyrism
  • Lathyrism is one of the oldest known neurotoxic disorders.
  • It’s a skeletal disorder caused by the toxin BAPN, which inhibits the copper-containing enzyme lysyl oxidase