The recent spread of monkeypox to non-endemic countries has trained the spotlight on reemerging viruses such as buffalopox, which was first isolated in India.
- Since the first case in 1934 globally recorded in India, the country has seen several sporadic outbreaks.
- It is a zoonotic disease endemic to India.
- It has its root in smallpox vaccines. Live virus used to inoculate buffaloes to produce the smallpox vaccine in India evolved into buffalopox over time.
- It is caused by buffalopox virus (BPXV); it is a Poxviridae for which the natural host is buffalo.
- It is classified in the Orthopoxvirus (OPV)
- Symptoms: Lesions occur localized on the udder, teats, and inguinal region, over the parotid, and the base and inner surface of the ear and eyes.