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Narrow-Spectrum Antibiotics

Narrow-Spectrum Antibiotics:

Scientists recently found that FP 100 (Hygromycin A), a first-in-class, small molecule, narrow-spectrum antibiotic, successfully eradicates Fusobacterium nucleatum without harming the oral or gut microbiomes.

  • Narrow-Spectrum Antibiotics are classified as “narrow-spectrum” or “broad-spectrum” depending on the range of bacterial types they affect.
  • Narrow-spectrum antibiotics are active against a selected group of bacterial types.
  • They can act on either gram +ve or gram –ve but not both.
  • They are used for the specific infection when the causative organism is known.
  • They will not kill as many of the normal microorganisms in the body as the broad-spectrum antibiotics.
  • Because they target very specific bacteria, they don’t cause an increase in bacterial resistance and avoid the spread of drug-resistant infections.
  • Examples include Azithromycin, Clarithromycin, Erythromycin, etc.