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Stem Cell-derived Mitochondria Transplantation

Stem Cell-derived Mitochondria Transplantation:

Six children with rare disorders caused by deletion in the genomes of their mitochondria were successfully treated for the first time by Stem-cell derived Mitochondria Transplantation.

  • The process involved the mitochondrial transplant from donor mothers into children’s haematopoietic stem cells, which give rise to all types of blood cells.
  • Stem Cell-derived Mitochondria Transplantation involves the spontaneous mitochondrial transfer of the stem cell to rescue the injured cells or the injection of stem cell isolated mitochondria into the injured area to repair the damage.
  • Stem cells are the most primitive cells at the top of the origin of cell lines, and they have a high capacity for differentiation and self-renewal.
  • In addition, stem cells can differentiate into various tissues, organs, or functional cells of the human body; therefore, stem cells hold great promise for therapeutic tissue engineering and regenerative medicine.