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Kyasanur Forest Disease

Kyasanur Forest Disease:

A new point-of-care test has been found to be highly sensitive in the rapid diagnosis of Kyasanur Forest Disease (KFD).

  • This disease is also known as monkey fever.

Point-of-care Test:

  • It is developed by Indian Council of Medical Research (ICMR)-National Institute of Virology.
  • It includes a battery-operated Polymerase Chain Reaction (PCR) analyser, which is a portable, lightweight and universal cartridge-based sample pre-treatment kit and nucleic acid extraction device that aid in sample processing at the point of care.

Benefits:

  • It would be beneficial for the diagnosis of KFD as the outbreaks mainly happen in remote areas, where there is lack of well-equipped sample handling and laboratory testing facilities.
  • It would be useful in quick patient management and controlling further spread of the virus.

About Kyasanur Forest Disease:

  • It is caused by the Kyasanur Forest disease Virus (KFDV), which primarily affects humans and monkeys.
  • It was first identified in 1957 in a sick monkey from the Kyasanur Forest in Karnataka. Since then, between 400-500 human cases per year have been reported.
  • Eventually, KFD emerged as a grave public health problem spreading through the entire Western Ghats.
  • Transmission:
    • In nature, the virus is maintained mainly in hard ticks (Haemaphysalis spinigera), monkeys, rodents, and birds.
    • To humans, it may occur after a tick bite or contact with an infected animal (a sick or recently dead monkey).
  • Symptoms:
    • Characterized by chills, frontal headache, body ache, and high fever for five to 12 days with a case fatality rate of 3 to 5%.