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Gene-Editing In Embryos

Gene-Editing In Embryos:

A new study published in the journal Nature Communications has warned of the potential consequences of gene editing technology, which is still not fully understood.

Key findings:

  • Using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) to delete harmful disease-causing mutations could create more problems
  • CRISPR could lead to extensive gene copying from one parent to another, potentially increasing the risk of diseases
  • The extent of the DNA damage induced by CRISPR and how cells respond to it is still not fully known
  • The technology used to test gene-edited embryos could reduce the accuracy of genetic testing, leading to the misdiagnosis of embryos.
  • The researchers concluded that such limitations must be addressed before gene editing technology can be used.
  • Previously, a Chinese scientist who announced the birth of gene-edited twins in 2018, had used CRISPR to make the embryos resistant to the human immunodeficiency virus (HIV).

Gene-editing:

  • Genome editing (also called gene editing) is a group of technologies that allow genetic material to be added, removed, or altered at particular locations in the genome.