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Delta Variant Sub-Lineage AY.12 – COVID 19

Delta Variant Sub-lineage AY.12:

According to a report by the Indian SARS-CoV-2 Genomics Consortium (INSACOG), a new sub-lineage AY.12 of the Delta variant of Covid-19 that was recently classified in Israel is now being reported in many parts of India.

  • INSACOG is a multi-laboratory, multi-agency, Pan-India network to monitor genomic variations in the SARS-CoV-2 by a sentinel sequencing effort.
  • INSACOG has pointed out that several cases in India classified as Delta are now being reclassified as AY.12 and these numbers are under close watch.
  • The reclassification is primarily to assist micro-epidemiology and is not based on acquisition of significant mutations. Thus, it is not currently known whether AY.12 is clinically different from Delta.
  • While no worrying factors have been found linked to the AY.12, it has come on INSACOG’s radar as it is said to be driving the surge in Israel despite 60% vaccination in the country.

Delta Variant:

  • B.1.617.2—also termed the Delta variant—is believed to spread faster than other variants. The Delta variant is highly contagious, more than twice as contagious as previous variants.
  • It has birthed several sub-lineages called ‘Delta plus’ variants that bear most of its characteristic mutations but are different in other ways.